5 Facts you should know about

Sarcoidosis

It is most often defined by the presence of noncaseating granulomatous inflammation that occurs in the absence of infection, exposures, malignancy, or alternative immune-related disease

Lung and thoracic lymph nodes are most often involved, but any organ can be affected

Patients with multi-system involvement have a worse prognosis

The basis of treatment of sarcoidosis is regulation of the heightened immune response and suppression of granulomatous inflammation in order to prevent dangerous interference with organ function

Use of corticosteroids and other immunomodulatory agents is often modeled on how they are used in other autoimmune and inflammatory diseases in which suppression of the immune system is desired

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